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Consequently, 22q11DS is an appealing model as it allows us to: (1) elucidate specific genotypephenotype associations, (2) prospectively study behaviorally defined classifications, such as ASD or SSD, in the context of a known, well-characterized genetic basis, and (3) elucidate mechanisms underpinning variable penetrance and pleiotropy, phenomena with far-reaching ramifications for research and clinical practice

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References Bankhead, C

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